: estradiol benzoate

Synonyms: beta-Estradiol-3-benzoate; Oestradiol Benzoate; 17beta-Estradiol benzoate; 1,3,5(10)-Estratriene-3,17b-diol 3-benzoate; 3,17b-Dihydroxy-1,3,5(10)-estratriene 3-benzoate; (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate

CAS: 50-50-0

EINECS: 200-043-7

MF: C25H28O3

MW: 376.488

Assay: 99%

Appearance: White powder

Density 1.185g/cm3

Melting point 191-198℃

Boiling point 531.2°C at 760 mmHg

Refractive index 1.604

Flash point 212°C

Vapour Pressur 4.08E-12mmHg at 25°C

2.  Descriptions:

Estradiol benzoate (INN; brand names Agofollin, Diffolisterol, Progynon-B, many others), or oestradiol benzoate (BAN), is a synthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. It was the first form of estrogen to be marketed, patented by Schering-Kahlbaun in 1936 in an oil preparation for injectable use and introduced later that year as Progynon-B. Though it is still in widespread use today, it has been mostly superseded by newer forms of estradiol with improved pharmacokinetics that require less frequent administration such as estradiol cypionate and estradiol valerate.