Dapoxetine Hydrochloride

CAS No.: 129938-20-1

M.F.: C21H23NO HCl

M.W: 341.88

Appearance: White or almost white crystalline powder

Melting Point: 175.0°C~177.0°C

Specific Rotation: +128°±3

Loss on Drying: NMT 0.5%

Heavy metals: No Detectable

Relative Substance: Total impurity: NMT 0.1%

Assay: NLT 99.5%

Details:

Dapoxetine is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18 to 64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant